Hello Nyla,
Please read up on SN curves.
The Structural Steel used as the default material in every model has an SN curve defined.
Read up on the Fatigue Tool available in Mechanical.
https://ansyshelp.ansys.com/account/secured?returnurl=/Views/Secured/corp/v201/en/wb_sim/ds_Fatigue_Tool_o_r.html?q=fatigue
Here are the instructions for using the above link.
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