Note that AEDT2021R2 is not officially tested/supported on Windows 11. AEDT2022R2 was the first version certified on Windows 11. ref: https://www.ansys.com/it-solutions/platform-support
However, I am skeptical that is the reason for the failure.
Please try this: 1.. Use Add/Remove programs to uninstall AEDT 2021R2 2.. Completely delete the "C:\Program Files\AnsysEM\AnsysEM21.2" folder 3.. Use Add/Remove programs to uninstall each the "Microsoft Visual C++ 20xx" Redistributables 4.. Install AEDT again -- if possible, I suggest you use 2022R2
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New Post - Reply To: ConfigureThisMachine.exe failed with error code 259
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