George Karnos
Ansys Employee

Are you using the free student version or do you have the License Manager installed on the machine with a valid license?
What is your Workflow when opening PyAnsys(MAPDL)?
Can you post a screenshot of the error? What License is it erroring-out on?
When you look in %TEMP%\.ansys, you will see .out files.
These contain licensing debug information.
Check the debug for the the process you are running to see what errors it states. Please post that here.