Hi helene,
You can open the .aedt file and when the warning appears that it is open in another instant or related lock file click on continue.
This will not erase any saved data.
Before doing this you can copy the .aedt file and results folder into another location on your PC for backup.
This may happen due to memory issues also.
Please check the RAM nad memory details in Task manager while running the simulation.
Regards,
Navya