Hello,
you should aim for maximum Orthogonal quality to be below 0.9 and maximum skewness below 0.7-0.8. Also, your aspect ratio appears to be too large. Did you generate this mesh?
We have an Ansys Innovation Course on compressible flow over an airfoil Compressible Flow Over An Airfoil | Ansys Innovation Courses. There is a mesh file provided. Perhaps you could have a look at it as reference.
Bests,
Federico