APLD geometry creations is documented in the APDL Modeling and Meshing Guide. The approach I envision is to create the entire domain first with the BLOCK command and then slice it up with VSBW (Volume Subtract Work Plane). The location of the work plane is specified with the WPLANE command. After you have an initial position for the workplane it's easier to move it the next location with the WPOFF command. After you made the slices in one direction you would specify a new rotated workplane with WPLANE. So the commands would be:
/PREP7
BLOCK,...
WPLANE,...
VSBW,...
WPOFF,... ! Repeated commands could be in a *DO loop
VSBW,...
WPOFF,...
VSBW,...
WPLANE,... ! Rotated workplane
VSBW,...
...
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