Thank you for your reply and the links provided.

I am trying to simulate a biological tissue which is assumed as a semi-hemisphere (3D) with a thin thickness which is under internal pressure. Since the real material is composed of many fibers throughout the thickness, the uniaxial tension test results in the lab have shown that the stiffness of the tissue changes in radial direction through the tissue. (Actually the fibers near the outer part are more interweaving leading to the higher stiffness)

I already have a graph of young modulud and also shear modulus vs the radial position and I would like to apply them in my model. 

I would apprecaite any help.