Hello Nick, thank you for your reply. I would not say it is like a ball check valve. What I want to simulate is literally applying an oscillating rotational speed to a cylindrical chamber full of water with a bead in it.

I am not interested in deformation and stress. However, CFX or Fluent may not be sufficient because I do not think it would consider the interaction between the bead and the wall. I have tried 6 DOF, but when to bead approaches the wall, an error that says, "negative volume mesh detected", pops up.

I agree Rocky seems to solve a large number of spherical objects...