Rob
Ansys Employee

Polyflow uses a fundamentally different solver to Fluent and CFX, and is designed for extrusion modelling and fluids with visco-elastic properties and it's the numerical differences that make it take longer. If you're "just" needing to model a fluid with HB viscosity I'd suggest sticking with one of the CFD codes: my personal preference is Fluent, but CFX is equally capable.